Clinical–Morphological Features and Outcomes of Lupus Podocytopathy
نویسندگان
چکیده
منابع مشابه
Clinical-Morphological Features and Outcomes of Lupus Podocytopathy.
BACKGROUND AND OBJECTIVES Lupus podocytopathy, which is characterized by diffuse foot process effacement without peripheral capillary wall immune deposits and glomerular proliferation, has been described in SLE patients with nephrotic syndrome in case reports and small series. This study aimed to better characterize the incidence, clinical-morphologic features, and outcomes of such patients fro...
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More than one half of all patients with SLE will have clinically evident kidney disease, generally termed lupus nephritis (LN), at some point during their disease course. The diagnosis and management of LN have improved remarkably over the last three decades enhanced by (1) a refined and reproducible classification scheme for the diverse glomerulopathies associated with SLE, (2) a number of epi...
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Lupus nephritis (LN) is usually associated with immune deposition in the glomerular capillary wall. On the other hand, focal segmental glomerulosclerosis (FSGS) is not typically associated with immune deposition, and its pathogenesis includes podocyte damage and loss. The definition of lupus podocytopathy (LP) excludes patients with electron-dense glomerular basement membrane deposits. Here, we...
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Podocytopathy in systemic lupus erythematosus is characterised by diffuse foot process effacement without significant peripheral capillary wall immune deposits as seen on electron microscopy. Lupus podocytopathy falls outside the scope of the current International Society of Nephrology and the Renal Pathology Society classification of lupus nephritis. We present a case of relapsing podocytopath...
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ژورنال
عنوان ژورنال: Clinical Journal of the American Society of Nephrology
سال: 2016
ISSN: 1555-9041,1555-905X
DOI: 10.2215/cjn.06720615